Births using sperm retrieved via immediate microdissection of a solitary testis with cancer.

Objective: To determine the feasibility of achieving births using sperm retrieved from a solitary testis with cancer.

Design: Prospective clinical study of azoospermic men with testis cancer in a solitary testis.

Setting: Infertility patients in an academic environment.

Ovarian hyperstimulation and oophorectomy following accidental daily clomiphene citrate use over three consecutive months.

We describe the longest-known continuous use of clomiphene citrate ever reported in a human. As a result of a pharmacy error, a woman took 50 mg/day clomiphene citrate for three months. The prolonged use of this medication resulted in ovarian hyperstimulation and unilateral oophorectomy for torsion.

Shared oocyte donation: society's benefits.

Objective: To assess the efficacy of oocyte donation when a cohort of oocytes is shared between two phenotypically matched recipients.

Design: A retrospective analysis of a program using shared anonymous oocyte donation.

Setting: Academic infertility center.

Human zona pellucida micromanipulation and monozygotic twinning frequency after IVF.

To assess the association of zona pellucida micromanipulation and subsequent development of monozygotic twins, cases of assisted embryo hatching (AH) and intracytoplasmic sperm injection (ICSI) were identified and related to treatment type, implantation and zygosity data. Embryology records from all patients undergoing in-vitro fertilization (IVF) at this centre from January 1995 to March 1998 were reviewed. In this study, 3546 transfer cycles were completed, with clinical pregnancy established in 1911 (54% per transfer) patients undergoing a single IVF cycle.