Publications by authors named "M Molls"
Purpose: Non-small cell lung cancer (NSCLC) is a fatal disease with poor prognosis. A membrane-bound form of Hsp70 (mHsp70) which is selectively expressed on high-risk tumors serves as a target for mHsp70-targeting natural killer (NK) cells. Patients with advanced mHsp70-positive NSCLC may therefore benefit from a therapeutic intervention involving mHsp70-targeting NK cells.
View Article and Find Full Text PDFAim: To report long-term data regarding biochemical control and late toxicity of simultaneous integrated boost intensity modulated radiotherapy (SIB-IMRT) with tomotherapy in patients with localized prostate cancer.
Background: Dose escalation improves cancer control after curative intended radiation therapy (RT) to patients with localized prostate cancer, without increasing toxicity, if IMRT is used.
Materials And Methods: In this retrospective analysis, we evaluated long-term toxicity and biochemical control of the first 40 patients with intermediate risk prostate cancer receiving SIB-IMRT.
Purpose: To evaluate outcome in patients with base of skull meningiomas treated with modern high precision radiation therapy (RT) techniques.
Patients And Methods: 927 patients from three centers were treated with either radiosurgery or fractionated high-precision RT for meningiomas. Treatment planning was based on CT and MRI following institutional guidelines.
Article Synopsis
- - X-ray microbeam radiotherapy has the potential to improve treatment effectiveness by redistributing the radiation dose more favorably, but current technologies are limited to expensive synchrotron facilities due to their high requirements.
- - A new laser-based Compact Light Source was used to investigate this therapy in a way that could be more practical for clinical use, focusing on its impact on normal tissue cells after exposure to microbeam irradiation.
- - The results showed that microbeam irradiation led to higher cell survival rates and fewer chromosome abnormalities compared to traditional radiation methods, suggesting it could reduce normal tissue damage and the risk of developing secondary cancers.
Background And Purpose: The aim of the present study was to evaluate if it is feasible for experienced radiation oncologists to visually sort out patients with a large dose to the heart. This would facilitate large retrospective data evaluations. And in case of an insufficient visual assessment, to define which structures should be contoured and which structures can be skipped as their dose can be derived from other easily contoured structures for future clinical trials.
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