Salbutamol attenuates arrhythmogenic effect of aminophylline in a hPSC-derived cardiac model.

The combination of aminophylline and salbutamol is frequently used in clinical practice in the treatment of obstructive lung diseases. While the side effects (including arrhythmias) of the individual bronchodilator drugs were well described previously, the side effects of combined treatment are almost unknown. We aimed to study the arrhythmogenic potential of combined aminophylline and salbutamol treatment in vitro.

Bioactive Carbon@CeO Composites as Efficient Antioxidants with Antiamyloid and Radioprotective Potentials.

Blending carbon particles (CPs) and nanoscale bioactive cerium dioxide is a promising approach for designing composites for biomedical applications, combining the sorption and antioxidant potentials of each individual component. To address this issue, it is crucial to assess the correlation between the components' ratio, physicochemical parameters, and biofunctionality of the composites. Thus, the current research was aimed at fabricating C@CeO composites with different molar ratios and the examination of how the parameters of the composites affect their bioactivity.

Probabilistic Analysis of Critical Speed Values of a Rotating Machine as a Function of the Change of Dynamic Parameters.

Real-world rotordynamic systems exhibit inherent uncertainties in manufacturing tolerances, material properties, and operating conditions. This study presents a Monte Carlo simulation approach using MSC Adams View and Adams Insight to investigate the impact of these uncertainties on the performance of a Laval/Jeffcott rotor model. Key uncertainties in bearing damping, bearing clearance, and mass imbalance were modeled with probabilistic distributions.

Biocompatible Hydrogel-Based Liquid Marbles with Magnetosomes.

Liquid marbles are widely known for their potential biomedical applications, especially due to their versatility and ease of preparation. In the present work, we prepared liquid marbles with various cores composed of water, agar-based hydrogels, magnetic fluids, or non-aqueous substances. As a coating material, we used biocompatible particles of plant origin, such as turmeric grains and pollen.

Tuning of Magnetic Hyperthermia Response in the Systems Containing Magnetosomes.

A number of materials are studied in the field of magnetic hyperthermia. In general, the most promising ones appear to be iron oxide particle nanosystems. This is also indicated in some clinical trial studies where iron-based oxides were used.