Publications by authors named "M Modat"

Background: COVID-19 symptoms may persist beyond acute SARS-CoV-2 infection, as ongoing symptomatic COVID-19 [OSC] (symptom duration 4-12 weeks) and post-COVID syndrome [PCS] (symptom duration ≥12 weeks). Vaccination against SARS-CoV-2 decreases OSC/PCS in individuals subsequently infected with SARS-CoV-2 post-vaccination. Whether vaccination against SARS-CoV-2, or any other vaccinations (such as against influenza) affects symptoms in individuals already experiencing OSC/PCS, more than natural symptom evolution, is unknown.

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Purpose: Subarachnoid haemorrhage is a potentially fatal consequence of intracranial aneurysm rupture, however, it is difficult to predict if aneurysms will rupture. Prophylactic treatment of an intracranial aneurysm also involves risk, hence identifying rupture-prone aneurysms is of substantial clinical importance. This systematic review aims to evaluate the performance of machine learning algorithms for predicting intracranial aneurysm rupture risk.

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  • AI is revolutionizing medical imaging for metabolic bone diseases (MBDs) like osteoporosis and rare conditions, enhancing diagnosis and management.
  • The article analyzes various AI techniques, recent advancements, and their clinical applications, while addressing ethical issues and future developments.
  • By combining AI with existing imaging methods, there is potential for improved diagnostic accuracy and patient outcomes in the treatment of MBDs.
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  • Data preprocessing is essential in deep learning, especially in computer vision, but traditional methods can lead to inefficiencies, image quality degradation, and added complexity, particularly in medical imaging.
  • Lazy Resampling offers a solution by consolidating multiple spatial preprocessing operations into a single step, minimizing execution time and signal loss, while simplifying the design of preprocessing pipelines.
  • Evaluations show that Lazy Resampling reduces information loss and enhances label accuracy, resulting in improved performance for semantic segmentation tasks when training models like UNets.
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Background: Predicting diabetic retinopathy (DR) progression could enable individualised screening with prompt referral for high-risk individuals for sight-saving treatment, whilst reducing screening burden for low-risk individuals. We developed and validated deep learning systems (DLS) that predict 1, 2 and 3 year emergent referable DR and maculopathy using risk factor characteristics (tabular DLS), colour fundal photographs (image DLS) or both (multimodal DLS).

Methods: From 162,339 development-set eyes from south-east London (UK) diabetic eye screening programme (DESP), 110,837 had eligible longitudinal data, with the remaining 51,502 used for pretraining.

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