Increased copeptin may reflect vasopressin-related metabolic changes after bariatric surgery.

Objective: Mechanisms underlying metabolic improvement following metabolic and bariatric surgery (MBS) may provide insight into novel therapies. Vasopressin improves body composition and protects against hypoglycemia. Associations of copeptin, a stable cleavage product of vasopressin, with BMI and insulin resistance suggest an adaptive increase in vasopressin to counteract metabolic disruption.

Outcomes following laparoscopic adrenalectomy: Experience of more than two decades at a tertiary care centre.

Introduction: Laparoscopic transperitoneal adrenalectomy was first described by Gagner M et al. Here, we present our experience of more than two decades of laparoscopic adrenalectomy performed in a single surgical unit at a tertiary care centre.

Patients And Methods: A prospectively collected database of patients undergoing laparoscopic adrenalectomy from December 1994 to May 2020 was analysed retrospectively.

Dialysis Jeopardy!

Dialysis Jeopardy! was a fun and innovative dialysis quiz for conference attendees at the Annual Dialysis Conference 2024 held in San Diego. The event saw active participation from nephrology fellows, faculty, and allied health care professionals. The event provided an excellent opportunity for nephrology fellows to interact with faculty in a nonformal setting.

IRGQ-mediated autophagy in MHC class I quality control promotes tumor immune evasion.

The autophagy-lysosome system directs the degradation of a wide variety of cargo and is also involved in tumor progression. Here, we show that the immunity-related GTPase family Q protein (IRGQ), an uncharacterized protein to date, acts in the quality control of major histocompatibility complex class I (MHC class I) molecules. IRGQ directs misfolded MHC class I toward lysosomal degradation through its binding mode to GABARAPL2 and LC3B.

Color Tunable Three Terminal (3-T) Vertically Stacked Tandem Organic Electroluminescent Devices.

Traditional full-color displays typically use a pixel layout with three side-by-side subpixels emitting red (R), green (G), and blue (B) colors. However, this configuration limits the resolution especially in augmented reality (AR) and virtual reality (VR) applications. To address the issue of low pixel density in display technology, this study demonstrated vertically stacked three-terminal (3-T) bottom-emitting tandem OLEDs (sOLED).