Publications by authors named "M Mirabelli"
Background: Hashimoto's thyroiditis (HT) is a common autoimmune thyroid disorder characterized by elevated anti-thyroid peroxidase (A-TPO) antibodies. HT frequently coexists with other autoimmune conditions, which are marked by organ-specific and non-organ-specific autoantibodies, reflecting a deregulated immune response. However, the burden and clinical significance of these circulating autoantibodies in adult patients with HT remains unclear.
View Article and Find Full Text PDFInsulin resistance (IR), marked by reduced cellular responsiveness to insulin, and obesity, defined by the excessive accumulation of adipose tissue, are two intertwined conditions that significantly contribute to the global burden of cardiometabolic diseases. Adipose tissue, beyond merely storing triglycerides, acts as an active producer of biomolecules. In obesity, as adipose tissue undergoes hypertrophy, it becomes dysfunctional, altering the release of adipocyte-derived factors, known as adipokines.
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- Women who had gestational diabetes (GDM) in their first pregnancy are likely to have it again in their next, but even those without previous GDM can develop it later.
- A study involving 759 women examined their GDM history in two pregnancies and categorized them based on their glucose tolerance status.
- Key predictors for developing GDM included family history, pregravid obesity, and specific glucose levels during the first OGTT, highlighting that higher glucose levels in the first pregnancy significantly raise the risk of GDM in subsequent pregnancies.
Introduction: Exposure to ambient air pollution can worsen cardiovascular disease and increase the risk of stroke, myocardial infarction, and cardiovascular disease mortality. Strategies to reduce air pollution exposure can therefore help prevent cardiovascular morbidity and mortality. This study was conducted to assess the awareness among U.
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