Publications by authors named "M Miqdady"

Background: Acute fulminant liver failure rarely occurs in the neonatal period. The etiologies include viral infection (15%), metabolic/genetic disease (10%), hematologic disorders (15%), and ischemic injury (5%). Gestational alloimmune liver disease usually manifests as severe neonatal liver failure, with extensive hepatic and extrahepatic iron overload, sparing the reticuloendothelial system.

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Eosinophilic esophagitis (EoE) is a chronic, progressive, type 2 inflammatory esophageal disease presenting as dysphagia to solid food and non-obstructive food impaction. Knowledge gaps exist in its diagnosis and management. These expert recommendations focused on the diagnosis of EoE in the United Arab Emirates.

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Article Synopsis
  • Wolcott-Rallison syndrome is a rare genetic disorder characterized by neonatal diabetes and various health complications, including liver impairment and growth issues, with a significant impact on patient survival rates.
  • A review of 62 studies involving 159 patients revealed a median age of presentation at 2.5 months and an average age of death at 36 months, with liver failure being a primary cause of mortality in some cases.
  • Transplantation, especially liver or multi-organ transplants, notably improves survival outcomes, with better prognosis linked to specific genetic mutations (missense mutations).
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Article Synopsis
  • When children can't get enough nutrition through oral feeding, enteral tube feeding becomes essential for their growth and quality of life.
  • Nasogastric tube feeding is typically used for short-term needs, while gastrostomy feeding is more convenient for long-term use after 2-3 weeks, according to guidelines.
  • Various methods for inserting gastrostomies exist, and the choice depends on patient needs and team expertise, emphasizing a personalized, multidisciplinary approach.
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Coronavirus disease 2019 (COVID-19) typically presents with fever and respiratory symptoms in children. Most children develop an asymptomatic and mild illness, with a minority requiring specialist medical care. Gastrointestinal manifestations and liver injury can also occur in children following infection.

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