Publications by authors named "M Millesimo"
Background: Despite evidence supporting use of fractional flow reserve (FFR) and instantaneous waves-free ratio (iFR) to improve outcome of patients undergoing coronary angiography (CA) and percutaneous coronary intervention, such techniques are still underused in clinical practice due to economic and logistic issues.
Objectives: We aimed to develop an artificial intelligence (AI)-based application to compute FFR and iFR from plain CA.
Methods And Results: Consecutive patients performing FFR or iFR or both were enrolled.
The quantification of stenosis severity from X-ray catheter angiography is a challenging task. Indeed, this requires to fully understand the lesion's geometry by analyzing dynamics of the contrast material, only relying on visual observation by clinicians. To support decision making for cardiac intervention, we propose a hybrid CNN-Transformer model for the assessment of angiography-based non-invasive fractional flow-reserve (FFR) and instantaneous wave-free ratio (iFR) of intermediate coronary stenosis.
View Article and Find Full Text PDFBackground: The prognostic impact of catheter ablation (CA) of atrial fibrillation (AF) in hypertrophic cardiomyopathy (HCM) patients has not yet been satisfactorily elucidated.
Objectives: The aim of the study was to assess the impact of CA of AF on clinical outcomes in a large cohort of HCM patients.
Methods: In this retrospective multicenter study, 555 HCM patients with AF were enrolled, 140 undergoing CA and 415 receiving medical therapy.
Article Synopsis
- Brugada syndrome presents management difficulties, especially for asymptomatic patients with the Brugada ECG pattern, and this study aimed to analyze the long-term outcomes of a large group of these individuals.
- A total of 1,149 asymptomatic patients with Brugada ECG were monitored over 2 to 22 years, revealing an overall low annual arrhythmic event rate of 0.2%, with slightly higher risks observed in those with spontaneous type-1 Brugada ECG.
- The findings suggest that asymptomatic patients generally have a low risk of serious cardiac events, highlighting the need for careful monitoring and potential individual risk assessments rather than a one-size-fits-all approach.
A 75-year-old man with a previous mitral valve repair experienced embolization of a left atrial appendage occlusion device in the left atrium. The device was successfully retrieved using a double snaring technique, without the need for open surgery. This is an unusual report of left atrial appendage occluder retrieval, confirming the feasibility of the technique and the high flexibility of the device.
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