Publications by authors named "M Mikulska"
Bloodstream infections (BSI) are frequent complications after allogeneic hematopoietic cell transplant (HCT). This study reports data on pre-engraftment BSI in years 2016-2021 and analyses changes in incidence, aetiology, resistance and mortality compared with two previous periods (2004-2009 and 2010-2015). In years 2004-2021, 1364 patients received HCT.
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- Kaposi sarcoma herpesvirus/human herpesvirus-8 (HHV-8) poses serious health risks for solid organ transplant recipients, with higher seroprevalence noted in recipients (8.4%) compared to donors (3.3%).
- Among transplant patients, a specific group of donors (D+) and recipients (R-) showed notable rates of HHV-8-related diseases, like Kaposi sarcoma (KS) and associated inflammatory cytokine syndrome (KICS), emphasizing the importance of careful monitoring.
- Effective management of HHV-8 diseases, such as KICS, suggests that treatment options like rituximab can significantly impact patient outcomes, highlighting the need for serologic screening and timely interventions.
Purpose Of Review: The purpose of this review is to report the available evidence regarding the use of combination regimens of antivirals and/or antibody-based therapy in the treatment of SARS-CoV-2 in immunocompromised patients.
Recent Findings: Literature search identified 24 articles, excluding single case reports, which included mainly patients with hematological malignancies and/or B-cell depletion. Data were divided based on the timing and reason for administration of combination treatment, that is, early treatment to prevent progression to severe COVID-19 and treatment of prolonged or relapsed infection.
Introduction: Favipiravir (FVP) is an antiviral, targeting RNA-dependent RNA polymerase. We aimed to evaluate the efficacy of FVP as a treatment for COVID-19.
Methods: We conducted a retrospective study in two centers (San Martino University Hospital in Genova, Italy, and Marmara University Pendik Training and Research Hospital, Turkey).
Conducting advanced resuscitation requires medical personnel to carry out appropriately coordinated actions. Certain difficulties arise when it becomes necessary to conduct cardiopulmonary resuscitation (CPR) on two patients at the same time. The aim of this paper was to assess the actions of teams participating in emergency medicine championships in tasks related to simultaneous cardiac arrests in two patients.
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