Publications by authors named "M Miedziaszczyk"
Tacrolimus is metabolized in the liver with the participation of cytochrome P450 isoforms 3A4 and 3A5 (CYP3A4, CYP3A5). Omeprazole, unlike famotidine, is a substrate and inhibitor of CYP2C19, CYP3A4, CYP3A5 enzymes. The aim of the study is to compare the effect of omeprazole and famotidine on the tacrolimus concentration and the kidney transplant function.
View Article and Find Full Text PDFTurner syndrome (TS) is associated with thyroid disorders. Since the rate of thyroid disease among patients with this syndrome is significantly higher as compared to the general population, it seems vital to explore this particular area. This systematic and critical review was performed to evaluate thyroid function and autoimmunity in patients with Turner syndrome.
View Article and Find Full Text PDFMetabolic syndrome (MS) comprises several symptoms or disorders that significantly increase the risk of developing atherosclerosis and type 2 diabetes. This study aims to determine the direct impact of testosterone therapy on the components of MS; although excluding type 2 diabetes cases. The authors conducted a systematic literature search of PubMed, Scopus, and Cochrane databases without date limits, using keywords such as "testosterone therapy", "metabolic syndrome" and "men".
View Article and Find Full Text PDFAcute tubulointerstitial nephritis induced by intravesical bacillus Calmette-Guerin: a rare case of acute kidney injury.
Eur Rev Med Pharmacol Sci
September 2024
Article Synopsis
- Intravesical bacillus Calmette-Guerin (IVBCG) is a common therapy for high-risk urothelial cancers, typically causing mild side effects, but a rare case of acute renal failure from acute tubulointerstitial nephritis (ATIN) emerged following treatment.
- A 64-year-old male with high-grade papillary urothelial carcinoma experienced acute kidney injury and hematuria after his first IVBCG dose, with tests revealing significant kidney dysfunction and its related complications.
- The patient was treated with a combination of corticosteroids and antibiotics, requiring hemodialysis, and after two weeks, showed substantial recovery with improved kidney function.
Background: In November 2022, OpenAI released a chatbot named ChatGPT, a product capable of processing natural language to create human-like conversational dialogue. It has generated a lot of interest, including from the scientific community and the medical science community. Recent publications have shown that ChatGPT can correctly answer questions from medical exams such as the United States Medical Licensing Examination and other specialty exams.
View Article and Find Full Text PDF