Esophageal carcinoma cuniculatum is a rare histology and can be difficult to diagnose prior to resection. To date, there have been 28 cases of resected esophageal carcinoma cuniculatum reported. Herein we describe a case found in the stomach of a patient who previously underwent a Roux-en-Y gastric bypass surgery.
View Article and Find Full Text PDFBackground: Talquetamab (anti-G protein-coupled receptor family C group 5 member D) and teclistamab (anti-B-cell maturation antigen) are bispecific antibodies that activate T cells by targeting CD3 and that have been approved for the treatment of triple-class-exposed relapsed or refractory multiple myeloma.
Methods: We conducted a phase 1b-2 study of talquetamab plus teclistamab in patients with relapsed or refractory multiple myeloma. In phase 1, we investigated five dose levels in a dose-escalation study.
Objective: To describe immune responses following administration of experimental Salmonella Dublin siderophore receptor protein (SRP) vaccines in Holstein heifer calves with adequate passive antibody transfer.
Methods: Calves were randomly assigned to receive placebo, vaccination with S Dublin SRP in adjuvant A, or vaccination with S Dublin SRP in adjuvant B at 7 ± 3 days of age and 3 weeks later. Before each vaccination, 4 and 8 days after the second vaccination (postvaccination), and 61 to 91 days postvaccination, S Dublin antibody titers were measured.
Objective: Many hyperthyroid cats (15% to 50%) have concurrent chronic kidney disease (CKD) that is "masked" and will not become azotemic until after treatment. Previous studies reported that mild-to-moderate azotemic CKD after methimazole or thyroidectomy does not adversely affect survival. Our objective was to determine whether hyperthyroid cats with masked CKD rendered euthyroid with radioiodine (131I) have shorter survival than 131I-treated euthyroid cats that remain nonazotemic.
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