TCGEx: a powerful visual interface for exploring and analyzing cancer gene expression data.

Analyzing gene expression data from the Cancer Genome Atlas (TCGA) and similar repositories often requires advanced coding skills, creating a barrier for many researchers. To address this challenge, we developed The Cancer Genome Explorer (TCGEx), a user-friendly, web-based platform for conducting sophisticated analyses such as survival modeling, gene set enrichment analysis, unsupervised clustering, and linear regression-based machine learning. TCGEx provides access to preprocessed TCGA data and immune checkpoint inhibition studies while allowing integration of user-uploaded data sets.

Zinc Sulfur Nanoparticles Cause Both the Negatory Vitality and Bioaccumulation on Gammarus pulex.

In recent years, Zinc Sulphur Nanoparticles (ZnS-NPs) have a wide range of applications such as in optical sensor, solid state solar window layers, photoconductors, phosphors and catalysts. There are no clear data on the waste-enriching effects of this nanoparticle, whose annual consumption is over million tons, and concerns remain unanswered. This research was also designed to investigate lethal and sublethal toxicity, as well as survivability and bioaccumulation on Gammarus pulex for the effects of possible waste products of ZnS-NPs.

Risk factors for surgery in children with ureteropelvic junction obstruction due to antenatally detected ınfantil hydronephrosis.

Background: Although the majority of cases with antenatally detected hydronephrosis (ANH) resolve during postnatal period; patients should be monitored for the risk of developing ureteropelvic junction obstruction (UPJO) which requires surgical intervention. We aimed to define independent risk factors for operation in whom diagnosis of UPJO was precisely proven with histopathological evidence.

Methods: Medical files of 155 children (186 renal units) with anteroposterior pelvic diameter (APPD) ≥ 7 mm or ≥ 1SFU (Society of Fetal Urology) grade of pelvicalyceal dilatation were retrospectively investigated.

Establishing an interhospital ECMO-transport program during a pandemic: Key lessons learned.

Background: The emergence of COVID-19 has amplified the importance of efficient patient transfer, leading to the idea of inter-hospital ECMO transport programs. However, there are limited studies on ECMO transfer protocols and experiences during COVID pandemic. This study aimed to evaluate the effectiveness our transport program and provide insights into establishing and maintaining ECMO programs.