Publications by authors named "M Merialdi"
Preterm birth (PTB), defined as the birth of a child before 37 completed weeks gestation, affects approximately 11% of live births and is the leading cause of death in children under 5 years. PTB is a complex disease with multiple risk factors including genetic variation. Much research has aimed to establish the biological mechanisms underlying PTB often through identification of genetic markers for PTB risk.
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- - The study investigates the genetic factors influencing the timing of parturition, finding 22 genetic loci associated with gestational duration from a large sample of almost 200,000 participants.
- - A meta-analysis of preterm delivery cases identified six genetic loci and highlighted similarities between genetic influences on gestational duration and preterm birth.
- - The research reveals that maternal genetics play a significant role in gestational timing, with some variants negatively impacting fetal birth weight, indicating a complex interaction between maternal and fetal genetics.
Indirect effect of COVID-19 on maternal mortality in Chile.
J Matern Fetal Neonatal Med
December 2023