Publications by authors named "M Merashli"

Sarcoidosis is an inflammatory multisystem disease characterised by non-necrotising granulomas that typically affect the lungs, lymph nodes, eyes, skin, liver, spleen, heart, bones and joints. Although rare, necrotising granulomas can also occur. In this report, we present a case of a healthy woman in her 60s who presented with a 1-year history of fatigue and generalised body aches.

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Article Synopsis
  • A 53-year-old male developed painful necrotic patches on both ankles two weeks after his second dose of the Pfizer COVID-19 vaccine, leading to a diagnosis of leukocytoclastic vasculitis based on a punch biopsy.
  • Despite normal vascular assessments, the patient experienced worsening ulcers and fever two months later, leading to the need for surgical debridement and treatment for multidrug-resistant bacteria.
  • The case emphasizes the potential severity of vaccine-associated leukocytoclastic vasculitis, underlining the importance for healthcare providers to investigate sudden skin lesions that may arise post-vaccination.
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Background: Primary antiphospholipid syndrome (PAPS) has been associated with an increase in clinical events associated with atherosclerotic vascular disease. Intima media thickness (IMT) of carotid arteries is a surrogate marker of atherosclerotic vascular disease.

Objectives: To conduct a systematic review and meta-analysis of studies evaluating IMT and their clinical correlates in PAPS.

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Objectives: To perform a meta-analysis on articles evaluating the common femoral vein wall thickness (VWT) in Behcet's disease and its possible clinical, laboratory and treatment correlates (BD).

Methods: Systematic search of EMBASE and PubMed databases from inception to October 2023; we employed random effect meta-analyses for continuous outcomes.

Results: The meta-analysis included 9 case-control and 1 cohort study: the VWT was greater in BD (n = 650) than in controls (n = 396) (p < 0.

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