Publications by authors named "M Mengel"
The XVI-th Banff Meeting for Allograft Pathology was held in Banff, Alberta, Canada, from 19th-23rd September 2022, as a joint meeting with the Canadian Society of Transplantation. To mark the 30 anniversary of the first Banff Classification, pre-meeting discussions were held on the past, present, and future of the Banff Classification. This report is a summary of the meeting highlights that were most important in terms of their effect on the Classification, including discussions around microvascular inflammation and biopsy-based transcript analysis for diagnosis.
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- The study focused on analyzing RSV infection risks in children under 24 months in Valladolid from 2010 to 2022, comparing these risks with those of influenza and COVID-19.
- It involved a retrospective cohort study of 1,507 RSV cases, revealing that hospitalized RSV patients were generally younger and had lower comorbidity rates than those with influenza or COVID-19.
- Key findings indicated that factors like prematurity, maternal smoking, and coinfection increased the risk of severe RSV outcomes, while breastfeeding and complete vaccination were protective against hospitalization and severity.
Article Synopsis
- * There are big differences in climate risks if we exceed temperature limits versus if we stay within them, including effects on sea levels and ice.
- * To prevent dangerous climate changes, we need to find ways to remove a lot of carbon dioxide from the atmosphere, but this could be hard and expensive to do, meaning we need to act quickly to cut emissions instead.
Isolated v-lesion presents diagnostic stratification and clinical challenges. We characterized allograft outcomes for this entity based on posttransplant time (early: ≤1 month vs late: >1 month) and compared its molecular phenotype with other v+ rejection forms. Using the NanoString B-HOT panel, we analyzed 92 archival formalin-fixed paraffin-embedded tissue kidney biopsies from 3 centers: isolated v-lesion (n = 23), antibody-mediated rejection (ABMR) v+ (n = 26), T cell-mediated rejection (TCMR) v+ (n = 10), mixed rejection v+ (n = 23), and normal tissue (n = 10).
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