Publications by authors named "M Memis"
Impact of mild traumatic brain injury (mTBI) on sperm genome integrity: insights from a mouse model.
J Endocrinol Invest
March 2025
Purpose: Traumatic Brain Injury (TBI) poses a significant global health burden, with Mild TBI (mTBI) being the most prevalent form. TBI triggers activation of the hypothalamic-pituitary-adrenal (HPA) axis, which in turn affects the hypothalamic-pituitary-gonadal (HPG) axis regulating oogenesis and spermatogenesis. In this study, we investigated the impact of mTBI on sperm genome integrity using a repetitive mTBI (r-mTBI) mouse model.
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- The study investigates the link between Behçet's disease (BD) and apical periodontitis (AP), noting that this correlation hasn't been explored before.
- It involved 98 participants (49 with BD and 49 controls), where AP presence was assessed through clinical and radiographic methods, considering different factors like medication and disease severity.
- Results showed a higher prevalence of AP in BD patients compared to controls, indicating a significant association, but the effectiveness of endodontic treatments for BD patients was similar to that of healthy individuals.
Article Synopsis
- Traumatic brain injury (TBI) is a serious issue that can cause death and make people very sick, affecting not just the brain but also the kidneys and liver.
- Researchers wanted to study how the body's response to TBI affects these organs, especially by looking at certain markers that show inflammation and cell processes after the injury.
- In an experiment with mice, they found different reactions in male and female mice's liver and kidney tissues after mild TBI, suggesting that the injury impacts the body in various ways and depends on the sex of the mice.
The aims of this study were to determine the miRNAs involved in the methanol poisoning, and identify the male- and female-specific miRNA expression patterns in mice. Methanol was applied orally at the doses of 4 g/kg and 8 g/kg to induce mild and severe methanol poisoning in Balb/c mice. miRNA expression levels were detected at 3 different time periods (30, 60, and 180 min) following methanol exposure.
View Article and Find Full Text PDFAutosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of chronic kidney disease with () 1 and 2 gene mutation. However, the intra-familial variability in symptoms further suggests a non-Mendelian contribution to the disease. Our goal was to find a marker to track the epigenetic changes common to rapidly progressing forms of the disease.
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