Noise-sensitivity during sleep in non-sedated mechanically ventilated patients is associated with weaning duration: a polysomnographic study.

Background: Poor sleep is a major concern in intensive care units (ICUs), particularly in mechanically ventilated patients, because it is associated with longer duration of the weaning phase and higher mortality. High noise levels in ICUs are frequently reported by patients as one of the most disturbing sleep-disrupting factors but would be responsible for less than 20% of arousals. This suggests major inter-individual variability in noise sensitivity.

Modeling ventilation of patients with interstitial lung disease at rest and exercise: a bench study.

Background: The ventilatory physiopathology of patients with interstitial lung disease (ILD) remains poorly understood. We aimed to personalize a mechanical simulator to model healthy and ILD profiles ventilation, and to evaluate the effect of spontaneous breathing on respiratory mechanics at rest and during exercise.

Methods: In a 2-compartment lung simulator (ASL 5000), we modeled 1 healthy and 3 ILD profiles, at rest and during exercise, based on physiological data from literature and patients.

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Introducción: El enojo es frecuente en los trastornos emocionales y se asocia a mayor severidad y peor respuesta al tratamiento. Las intervenciones realizadas desde la terapia dialéctico comportamental (DBT) pueden ser eficaces para lograr un manejo efectivo del enojo. El objetivo del trabajo fue determinar la efectividad de participar de un grupo de entrenamiento en habilidades para el manejo efectivo del enojo.

Hypoxic burden and sleep hypoventilation in obese patients.

Introduction: Novel biomarkers of hypoxic load have emerged, as sleep apnea-specific hypoxic burden which provides more precise assessment of intermittent hypoxemia severity. Our main objective was to assess the potential benefit of hypoxic burden to identify obesity-related sleep hypoventilation. We hypothesized that hypoxic burden may help diagnose obesity-related sleep hypoventilation better than usual sleep respiratory measures (i.