Publications by authors named "M Mehrali"
callus contains pluripotent stem cells, and its extract (HPCE) is a natural compound that includes various biologically active components, such as phenolic acids, flavonoids, and naphthodiantrons like hypericin and hyperforin. These components give HPCE significant antibacterial and antioxidant properties, making it a valuable option for wound healing. Unlike traditional wound dressings that may leave a residue or necessitate invasive procedures like phototherapy, HPCE is a promising alternative.
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- Plant callus, particularly from Hypericum perforatum, is rich in beneficial compounds like hyperforin and hypericin that have antibacterial and anti-inflammatory properties, making them useful for wound healing.
- A new wound dressing made from poly(vinyl alcohol), chitosan, and alginate is infused with Hypericum perforatum callus extract (HPCE) and has shown favorable properties such as high swelling capacity and mechanical strength, enhancing tissue regeneration.
- In laboratory and animal studies, this dressing has been proven to be biocompatible, promote healing processes like re-epithelialization and collagen deposition, and reduce the risk of fibrosis after wounds heal, while also combating antibiotic-resistant bacteria.
Chronic wounds are a critical and costly complication that affects millions of patients each year, especially patients suffering from diabetes, and constitute a serious global healthcare problem that needs immediate attention. In this direction, novel dressings that can integrate appropriate physicochemical and biological features, mechanical durability, and the capacity for therapy are of great clinical importance. For instance, self-healable hydrogels, with antibacterial activity and high tissue adhesion, have attracted increasing attention for wound management applications.
View Article and Find Full Text PDFBackground: Acne is a chronic inflammatory skin disease that negatively affects patients' quality of life. Increasing antibiotic resistance is making acne less responsive to treatment. Probiotics are live microorganisms that can provide health benefits by fighting pathogens and maintaining intestinal homeostasis and skin microbiome balance.
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- Gel electrolytes provide a versatile alternative to liquid electrolytes in energy storage devices, enhancing safety, flexibility, and cost-effectiveness, with aqueous gels leading the way due to high ion solvation and conductivity.
- The main drawbacks of hydrogel electrolytes are their susceptibility to freezing and dehydration, which can impair EES device performance; however, a newly developed hydrogel system overcomes these issues with remarkable mechanical strength and antifreezing properties.
- This innovative hydrogel electrolyte shows impressive stability, maintaining high ionic conductivity and performance across a broad temperature range and various conditions, as demonstrated by its ability to power a wristwatch at 50 °C, suggesting strong potential for future EES applications.