Introduction: Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of sight-threatening infections in the US. These strains pose a significant challenge in managing ocular infections, as they frequently exhibit resistance to first-line empirical antibiotics. To assess the potential of bacteriophages as innovative topical therapies for treatment of recalcitrant ocular infections, we evaluated the in vitro antimicrobial activity of a set of anti-S.
View Article and Find Full Text PDFStatin pharmacogenetic implementation guidelines are derived from evidence of primarily Eurocentrically biased study populations. Functional SLCO1B1 variants that are rare in these study populations have not been equitably investigated and are thus missing from guidelines. The objective of this precision medicine health equity study was to determine the clinical validity of understudied candidate functional SLCO1B1 variants common in people with 1,000 Genomes sub-Saharan African superpopulation (1KG-AFR-like) genetic similarity.
View Article and Find Full Text PDFThe role of assessment in PharmD education and program accreditation continues to evolve with the release of the Curricular Outcomes and Entrustable Professional Activities (COEPA) and the Accreditation Council for Pharmacy Education Standards 2025. This special collection, titled the COEPA Curricular Assessment Blueprint and Needs Analysis, highlights best assessment practices related to each COEPA subdomain. The articles in this collection provide a blueprint for educators seeking a framework for designing and implementing assessment plans that achieve the expected outcomes for PharmD programs.
View Article and Find Full Text PDFObjective: Childbirth is a natural process, and according to the World Health Organization, oral intake is recommended for patients at usual risk. However, due to rare cases of pulmonary aspiration (known as Mendelson's syndrome) during general anesthesia and the limited evidence supporting its benefits, this practice remains controversial. This systematic review summarizes evidence on interventions that recommend oral intake during labor compared to fasting, focusing on labor duration and perinatal complications.
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