Impact of nocturnal oxygen enrichment on high-altitude acclimatization.

Nocturnal oxygen enrichment improves sleep at high altitudes but may impair acclimatization. Our purpose was to determine if nocturnal oxygen enrichment impacts acclimatization. A 7-day acclimatization protocol occurred at a field-based research site between 0 and 4,200 m.

The combined influences of local heat application and resistance exercise on the acute mRNA response of skeletal muscle.

Introduction: The development and maintenance of the skeletal muscle is crucial for the support of daily function. Heat, when applied locally, has shown substantial promise in the maintenance of the muscle. The purpose of this study was to determine the combined effects of local heat application and acute resistance exercise on gene expression associated with the human muscle growth program.

Echocardiograms and bed placement in patients with multisystem inflammatory syndrome in children.

Background: Understanding of multisystem inflammatory syndrome in children (MIS-C) continues to evolve with extensive evaluations, including echocardiograms, obtained in emergency departments (EDs) to assist with clinical decision making and bed allocation. We assessed the utility of obtaining echocardiograms in the ED to assist in determining bed placement for this patient population.

Methods: This 2-year retrospective single-center study of patients 0-21 years old without underlying cardiac disease hospitalized for MIS-C focused on individuals whose initial evaluation occurred in the institution's ED and whose echocardiogram was obtained either in the ED or within 24 hours of admission.