Publications by authors named "M Mazhar Ayaz"

Objective: There are variations in prognosis and therapeutic approach for renal cell carcinoma among different histological subtypes. This study aims to determine the relationship between radiologically detected peritumoral neovascularization and the histological subtypes of Renal Cell Carcinoma (RCC) and to assess whether extratumoral neovascularization characteristics detected via imaging can contribute to distinguishing these subtypes alongside tumor size and T-stage.

Materials And Methods: 104 renal tumors from 104 cases consisting of 31 females (29.

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Alzheimer's disease (AD), a progressiveneurodegenerative condition is marked by extensive damage in the brain and dementia. Among the pathological hallmarks of AD is beta-amyloid (Aβ). Production of toxic Aβ oligomers production and accumulation in the brain is among the characteristic features of the disease.

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: Inflammation and analgesia are two prominent symptoms and often lead to chronic medical conditions. To control inflammation and analgesia, many marketed drugs are in practice but the majority of them have severe side effects. : This study involved the synthesis of a pivalate-based Michael product and evaluated it for in vitro COX-1, COX-2, and 5-LOX inhibitory potentials using specific assays.

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Article Synopsis
  • Antiepileptic drugs (AED) are increasingly used for conditions beyond epilepsy, such as bipolar disorder and migraines, leading to a study on their prescribing patterns in pediatric, neurosurgery, and psychiatry wards.
  • Conducted at Ayyub Teaching Hospital from December 2018 to April 2019, the study analyzed data from 410 patients, finding that a majority were male (54.3%) and aged 1-18 years (63.7%), with most patients (96.1%) having additional health issues.
  • The study revealed that sodium valproate was the most prescribed AED (59.0%), but a significant 77.6% of prescriptions did not adhere to treatment guidelines, and
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  • Endodontic and periodontal tissues are interconnected, and pathologies in one can impact the other, leading to endo-perio lesions (EPLs) that were the focus of this study.
  • The research involved analyzing 2,170 teeth from Indian adults over 18, considering patient histories, dental examinations, and conducting radiographs to diagnose EPLs while using statistical methods to assess risk factors and relationships.
  • The study found a 29.49% prevalence of EPLs, pinpointing associations with age for different types of lesions, noting non-vital pulps in type 3 lesions, and identifying faulty restorations and occupational trauma as key risk factors.
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