Publications by authors named "M Mauermann"
Speech intelligibility declines with age and sensorineural hearing damage (SNHL). However, it remains unclear whether cochlear synaptopathy (CS), a recently discovered form of SNHL, significantly contributes to this issue. CS refers to damaged auditory-nerve synapses that innervate the inner hair cells and there is currently no go-to diagnostic test available.
View Article and Find Full Text PDFVasculitic neuropathy is caused by inflammatory destruction of nerve blood vessels resulting in nerve ischemia. Nerve vasculitis can be divided into two categories based on vessel size - large arteriole vasculitis (≥75 µm) and microvasculitis (<75 µm). Herein, we characterize the clinical features of nerve large-arteriole vasculitis compared to nerve microvasculitis.
View Article and Find Full Text PDFBackground And Objectives: Patients with typical anti-myelin-associated glycoprotein (anti-MAG) neuropathy have IgM-gammopathy, mimic distal chronic inflammatory demyelinating polyradiculoneuropathy (CIDP), and are treatment resistant. Anti-MAG patients go unrecognized when IgM-gammopathy is undetected or with atypical phenotypes. We investigated an optimal anti-MAG titration cutoff for excluding CIDP and the impact of IgM-gammopathy detection on neuropathy treatment evaluation without anti-MAG antibodies.
View Article and Find Full Text PDFBackground And Objectives: Neurolymphomatosis (NL) is characterized by lymphomatous infiltration of the peripheral nervous system presenting as the initial manifestation of a lymphoma (primary NL [PNL]) or in relapse of a known lymphoma (secondary NL [SNL]). This report details and compares the neurologic clinicopathologic characteristics of these 2 groups.
Methods: This retrospective study was performed on patients diagnosed with pathologically confirmed NL in nerve between January 1, 1992, and June 31, 2020.
Article Synopsis
- Peripheral neuropathy in patients with excessive alcohol consumption is frequently misdiagnosed due to the lack of clear biomarkers and underlying biases against those with alcohol use disorder (AUD).
- Various mechanisms, including nutrient deficiencies and oxidative stress, contribute to alcohol-related nerve toxicity, but symptoms often resemble those of chronic idiopathic neuropathy, complicating diagnosis.
- The stigma surrounding AUD can harm patient care, as biases in healthcare may lead to inadequate treatment and social isolation, highlighting the need for increased awareness and better clinical practices.