Cone-Beam CT Segmentation for Intraoperative Electron Radiotherapy Based on U-Net Variants with Transformer and Extended LSTM Approaches.

Artificial Intelligence (AI) applications are increasingly prevalent in radiotherapy, including commercial software solutions for automatic segmentation of anatomical structures for 3D Computed Tomography (CT). However, their use in intraoperative electron radiotherapy (IOERT) remains limited. In particular, no AI solution is available for contouring cone beam CT (CBCT) images acquired with a mobile CBCT device.

PSMA-Guided Imaging and Therapy of Advanced Adenoid Cystic Carcinomas and Other Salivary Gland Carcinomas.

SGCs are rare malignancies, accounting for less than 1% of all head and neck cancers [...

Particle therapy in gastrointestinal cancer-a narrative review.

Background And Objective: Radiation therapy is one of the main pillars in the treatment of gastrointestinal (GI) cancers, especially esophageal and anorectal malignancies. The worldwide standard of care is yet an irradiation with photons. Though not commonly used, charged particles offer some physical advantages with a highly conformal dose distribution, which allows an even better sparing of organs at risk.

Patterns of Temporal Lobe Reaction and Radiation Necrosis after Particle Radiotherapy in Patients with Skull Base Chordoma and Chondrosarcoma-A Single-Center Experience.

Background: The current study aims to evaluate the occurrence of temporal lobe reactions and identify possible risk factors for patients who underwent particle therapy of the skull base.

Methods: 244 patients treated for skull base chordoma ( = 144) or chondrosarcoma ( = 100) at the Heidelberg Ion Beam Therapy Center (HIT) using a raster scan technique, were analyzed. Follow-up MRI-scans were matched with the initial planning images.

Intensity-modulated radiotherapy for the management of primary and recurrent chordomas: a retrospective long-term follow-up study.

Background: Chordomas have a high risk of recurrence. Radiotherapy (RT) is required as adjuvant therapy after resection. Sufficient radiation doses for local control (LC) can be achieved using either particle therapy, if this technology is available and feasible, or intensity-modulated radiotherapy.