Herpes zoster central nervous system complication: An increasing trend of acute limbic encephalitis.

Varicella zoster virus (VZV) causes chickenpox as the primary infection and then becomes latent in the cranial and spinal ganglia. VZV can reactivate with aging, immunosuppression, stress, and other factors. In our series of 15 patients with herpes zoster (HZ) central nervous system complications (8 males and 7 females, ages 41-86 years), we identified several types of complications: acute encephalitis, vasculitis, meningitis, and cranial nerve palsies, with acute limbic encephalitis (ALE) ( = 5) being particularly noteworthy.

Identification of occult STLV-1 infection in Japanese macaques.

Background: Primate T-cell leukemia virus type 1 (PTLV-1) is classified into a genus Deltaretrovirus that persists in infected primates and can lead to adult T cell leukemia and inflammatory diseases. Unlike hepatitis viruses, it remains unclear whether PTLV-1 could cause occult infection, a rare latent infection status characterized by detectable provirus without accompanying antibody responses.

Methods: A longitudinal study was conducted to characterize mother-to-child transmission of simian T cell leukemia virus type 1 (STLV-1) in Japanese monkeys (JMs).

Japanese version of the cancer needs questionnaire-young people (CNQ-YP-J): translation and preliminary validation.

Background: Adolescent and young adult (AYA) patients with cancer experience complex physical and psychosocial development as well as diverse lifestyle changes. Therefore, each patient may have generation-specific needs. This study aimed to develop a Japanese version of the Cancer Needs Questionnaire-Young People (CNQ-YP), namely the CNQ-YP-J, and to verify its reliability and validity among Japanese AYA patients with cancer.

Identification of AK4 and RHOC as potential oncogenes addicted by adult T cell leukemia.

Adult T cell leukemia (ATL) is a highly aggressive T cell malignancy characterized by human T cell leukemia virus type 1 (HTLV-1) infection. ATL has a very poor prognosis and lacks satisfactory treatments; therefore, it is critical to identify potential targets in ATL cells in order to develop effective targeted therapeutics. Here, we report the identification of two oncogenes, AK4 and RHOC, as target genes of miR-455-3p, a tumor-suppressive microRNA in ATL patients.

Progressive subchondral bone cyst formation following autologous chondrocyte implantation with all-suture anchors: a Case Report with histological evaluation.

Background: Subchondral bone cysts (SBCs) can significantly impact the outcomes of cartilage repair procedures such as autologous chondrocyte implantation (ACI). However, the etiology and progression of SBCs following ACI remain poorly understood. This case report highlights a progressively enlarging SBC following ACI using all-suture anchors, treated with autologous osteochondral transplantation (AOT).