Production of Malheuran A, a Geranylated Flavonoid with Antimicrobial and Anti-Inflammatory Activities, in Hairy Root Cultures of .

Phenolic compounds, such as stilbenes and flavonoids, from spp. exhibit diverse biological activities, including antimicrobial, anti-inflammatory, and cytotoxicity properties. To this end, the objectives of this study were to establish hairy root cultures of and assess its capacity to produce these bioactive compounds.

Critical Role of Rubber Functionalities on the Mechanical and Electrical Responses of Carbon Nanotube-Based Electroactive Rubber Composites.

Carbon nanomaterials, particularly carbon nanotubes (CNTs), are widely used as reinforcing fillers in rubber composites for advanced mechanical and electrical applications. However, the influence of rubber functionality and its interactions with CNTs remains underexplored. This study investigates electroactive elastomeric composites fabricated with CNTs in two common diene rubbers: natural rubber (NR) and acrylonitrile-butadiene rubber (NBR), each with distinct functionalities.

CD4CD8 double-positive T cells in immune disorders and cancer: Prospects and hurdles in immunotherapy.

CD4 and CD8 T cells play critical roles in both innate and adaptive immune responses, managing and modulating cellular immunity during immune diseases and cancer. Their well-established functions have led to significant clinical benefits. CD4CD8 double-positive (DP) T cells, a subset of the T cell population, have been identified in the blood and peripheral lymphoid tissues across various species.

Associations between weather extremes and faecal contamination along pathogen transmission pathways in rural Bangladeshi households: a prospective observational study.

Background: Weather extremes are predicted to influence pathogen exposure but their effects on specific faecal-oral transmission pathways are not well investigated. We evaluated associations between extreme rain and temperature during different antecedent periods (0-14 days) and Escherichia coli along eight faecal-oral pathways in rural Bangladeshi households.

Methods: We used data from the WASH Benefits Bangladesh cluster-randomised controlled trial (NCT01590095).

Orbital and adnexal sarcoidosis: Clinical presentations and management outcomes.

Purpose: To present the clinical features and management outcomes in a series of patients with orbital and adnexal sarcoidosis.

Methods: This was a retrospective analysis of 19 histopathologically proven cases of orbital and adnexal sarcoidosis over the past ten years. The data analyzed included demographic details, clinical and imaging features, and management outcomes.