Publications by authors named "M Mascherpa"

Objective: Antenatal growth assessment using ultrasound aims to identify small fetuses that are at higher risk of perinatal morbidity and mortality. This study explored whether the association between suboptimal fetal growth and adverse perinatal outcome varies with different definitions of fetal growth restriction (FGR) and different weight charts/standards.

Methods: This was a retrospective cohort study of 17 261 singleton non-anomalous pregnancies at ≥ 24 + 0 weeks' gestation that underwent routine ultrasound at a tertiary referral hospital.

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Objective: Uteroplacental dysfunction may not only result in pre-eclampsia (PE) but also in preterm birth (PTB), small-for-gestational-age (SGA) birth and stillbirth. The aim of this study is to evaluate the positive predictive value (PPV) of first-trimester combined PE screening for all of these placenta-mediated adverse pregnancy outcomes.

Design: Retrospective cohort study.

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Objective: To evaluate whether routine mid-gestational uterine artery Doppler (UtAD) modifies the risk for preterm pre-eclampsia after first-trimester combined pre-eclampsia screening.

Design: Retrospective cohort study.

Setting: London Tertiary Hospital.

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Article Synopsis
  • The study investigated the presence of antiphospholipid antibodies (aPL) in pregnant women hospitalized with SARS-CoV-2, focusing on its potential impact on pregnancy and thrombotic complications.
  • Sixteen out of 151 women were found to have positive aPL, with a higher incidence of obstetric complications such as HELLP syndrome and preeclampsia associated with aPL positivity.
  • Overall, the findings suggest that while aPL were present, their frequency in pregnant women with COVID-19 remained similar to that in the general obstetric population.
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