Graphene oxide scaffolds promote functional improvements mediated by scaffold-invading axons in thoracic transected rats.

Millions of patients and their caretakers live and deal with the devastating consequences of spinal cord injury (SCI) worldwide. Despite outstanding advances in the field to both understand and tackle these pathologies, a cure for SCI patients, with their peculiar characteristics, is still a mirage. One of the most promising therapeutic strategies to date for these patients involves the use of epidural electrical stimulation.

Yellow Pitahaya ( Haw.): The Less Known of the Pitahayas.

Pitahaya or dragon fruit is an exotic fruit native to Mesoamerica and is cultivated in several regions of the world. In recent years, pitahaya has become increasingly in demand, firstly, for its good nutritional and organoleptic qualities and, secondly, for its richness in antioxidants and bioactive compounds. Spain has opted for new tropical crops, and among them, pitahaya is one of the most planted in recent years.

Statistical Mechanics of Directed Networks.

Directed networks are essential for representing complex systems, capturing the asymmetry of interactions in fields such as neuroscience, transportation, and social networks. Directionality reveals how influence, information, or resources flow within a network, fundamentally shaping the behavior of dynamical processes and distinguishing directed networks from their undirected counterparts. Robust null models are crucial for identifying meaningful patterns in these representations, yet designing models that preserve key features remains a significant challenge.

Dysplasia and Colorectal Cancer Surveillance in Ulcerative Colitis Patients in Latin America: Real-World Data.

Background: The prevalence of colorectal cancer (CRC) in patients with ulcerative colitis (UC) is higher than in the general population, in Latin America there is a progressive increase of UC, and information about CRC screening in inflammatory bowel disease (IBD) is scarce. The aim of this study was to analyze the findings of endoscopic surveillance of CRC in patients with IBD according to available technology.

Methods: Multicenter, cross-sectional, analytical study conducted in Latin American countries, in patients with UC, predominantly with more than 8 years of diagnosis and different degrees of disease activity.

Comprehensive Clinical and Genetic Characterization of a Spanish Cohort of 22 Patients With Bainbridge-Ropers Syndrome.

Bainbridge-Ropers Syndrome (BRPS) is a genetic condition resulting from truncating variants in the ASXL3 gene. The clinical features include neurodevelopmental and language impairments, behavioral issues, hypotonia, feeding difficulties, and distinctive facial features. In this retrospective study, we analyzed 22 Spanish individuals with BRPS, aiming to perform a detailed clinical and molecular description and establish a genotype-phenotype correlation.