Publications by authors named "M Marriott"
The continuous monitoring of oxygen saturation (SpO) and respiratory rates (RRs) are major clinical issues in many cardio-respiratory diseases and have been of tremendous importance during the COVID-19 pandemic. The early detection of hypoxemia was crucial since it precedes significant complications, and SpO follow-up allowed early hospital discharge in patients needing oxygen therapy. Nevertheless, fingertip devices showed some practical limitations.
View Article and Find Full Text PDFGay men report poorer body image than straight men, but no research has examined other dimensions of sexual identity (e.g., sexual attraction).
View Article and Find Full Text PDFArticle Synopsis
- - Cladribine (Mavenclad®) is an oral treatment for relapsing remitting multiple sclerosis (RRMS), but its effects on the immune system were previously unclear.
- - A Phase IV study with 41 RRMS patients showed that cladribine significantly reduced the count of certain monocytes and altered levels of cytokines, notably increasing CCL2 at week 1 post-treatment.
- - The study found that cladribine also affects the P2X7 receptor's activity, highlighting a new action mechanism that suggests further research into its potential use against other forms of MS and neurodegenerative diseases.
Amplifying Immune Responses: Microparticulate Vaccine Approach Against Breast Cancer.
Breast Cancer (Dove Med Press)
March 2024
Introduction: The study focuses on evaluating the immune responses generated by a novel microparticulate murine breast cancer vaccine.
Methods: The methodology included the use of a co-culture model of dendritic cells (DCs), and T-cells to evaluate the immunotherapeutic responses generated by the vaccine.
Results: The study observed that the dendritic cells expressed significantly higher levels of MHC I, MHC II, CD 40, and CD 80 cell surface markers in the presence of the vaccine microparticles than the controls (p<0.
Despite the available evidence identifying the high prevalence rates of potentially traumatic experiences in forensic populations, there is still a lack of evidence supporting the use of suitable assessment tools, especially for young males in custody. For services to identify, support, and offer trauma interventions to this cohort, practitioners require reliable and valid assessment tools. This systematic review (Open Science Framework registration: https://osf.
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