Publications by authors named "M Markham"

Article Synopsis
  • BAP1 mutations lead to a loss of function affecting cell cycle and DNA repair, making patients potentially responsive to PARP inhibitors like niraparib.
  • A phase II trial evaluated niraparib in patients with advanced tumors likely to have mBAP1 mutations, focusing on response rates, progression-free survival, and overall survival.
  • Despite not meeting the primary efficacy goal, some clinical benefits were observed in patients with confirmed mBAP1 mutations, suggesting the need for further research.
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A key challenge toward future quantum internet technology is connecting quantum processors at metropolitan scale. Here, we report on heralded entanglement between two independently operated quantum network nodes separated by 10 kilometers. The two nodes hosting diamond spin qubits are linked with a midpoint station via 25 kilometers of deployed optical fiber.

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Fear of cancer recurrence (FCR), cancer-distress, depression, and anxiety are prevalent concerns among women with gynecologic and other understudied cancers, especially among women of color and lower socioeconomic status (SES). Evidence indicates that mind-body interventions are effective in reducing such distress. This study evaluates (1) proof-of-concept of an integrated group yoga and psychological intervention in alleviating distress among women with gynecologic, gastrointestinal, and thoracic cancers and (2) differences in efficacy across social and economic factors.

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Article Synopsis
  • Western diets can cause problems like liver diseases, and people are eating less protein from animals.
  • A study looked at how a low-protein diet (LPD) helps mice fight liver damage when they get infected with bacteria.
  • The findings showed that LPD reduces inflammation and helps the immune system work better by changing how immune cells behave in the liver.
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Secure messaging (SM) is an important aspect of communication for patients with cancer. SM fosters patient-clinician communication and helps patients with symptom management and treatment support. However, patients are uncertain about how to phrase messages appropriately and have expressed the need for guidance.

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