It is well established that infants use various cues to find words within fluent speech from about 7 to 8 months of age. Research suggests that two main mechanisms support infants' speech segmentation: prosodic cues like the word stress patterns, and distributional cues like transitional probabilities (TPs). We tested 6-month-old German-learning infants' use of prosodic and statistical cues for speech segmentation in three experiments.
View Article and Find Full Text PDFBackground: Cancer has been associated with an increased risk of in-hospital mortality in CDI patients. However, data on delayed mortality in cancer patients with CDI are scarce.
Aim/objective: The aim of the present study was to compare outcomes between oncological patients and the general population with infection (CDI) after 90 days of follow-up.
Colloids Surf B Biointerfaces
January 2023
In this study, we assessed the capacity of a previously reported engineered liposomal formulation, which had been tested against model membranes mimicking the lipid composition of the HeLa plasma membrane, to fuse and function as a nanocarrier in cells. We used atomic force microscopy to observe physicochemical changes on the cell surface and confocal microscopy to determine how the liposomes interact with cell membranes and released their load. In addition, we performed viability assays using methotrexate as an active drug to obtain proof of concept of the formulation´s capacity to function as a drug delivery-system.
View Article and Find Full Text PDFThe 2016 cumulative incidence of infection (CDI) in Spain was reported by the European Center for Disease Control to be above the mean of other European countries. The aim of this multicenter prospective observational cohort study was to examine the risk factors that determine 90-day CDI recurrence in Catalonia, Spain. The study included 558 consecutive adults admitted to hospital who had a symptomatic, first positive CDI diagnosis.
View Article and Find Full Text PDFBackground: The incidence of catheter-related bloodstream infections (CRBSIs) has fallen over the last decade, especially in intensive care units (ICUs).
Aim: To assess the existence of concomitant trends in outcomes and to analyse the current risk factors for mortality.
Methods: A multicentre retrospective cohort study was conducted at 24 Catalan hospitals participating in the Surveillance of healthcare-associated infections in Catalonia (VINCat).