Spinal microcircuits go through multiphasic homeostatic compensations in a mouse model of motoneuron degeneration.

In many neurological conditions, early-stage neural circuit adaptation preserves relatively normal behavior. In some diseases, spinal motoneurons progressively degenerate yet movement remains initially preserved. This study investigates whether these neurons and associated microcircuits adapt in a mouse model of progressive motoneuron degeneration.

Microsatellite markers development and molecular fingerprinting of cashew cultivars.

Background: Cashew (Anacardium occidentale L.) is a widely cultivated tree with great economic significance. In cashew, several elite cultivars have been developed for commercial cultivation, which form the underpinning for the cashew-based industries and the several billion-dollar world trade.

GALADRIEL: A facility for advancing engineering science relevant to rep-rated high energy density physics and inertial fusion energy experiments.

Many current and upcoming laser facilities used to study high-energy-density (HED) physics and inertial fusion energy (IFE) support operating at high rep-rates (HRRs) of ∼0.1-10 Hz, yet many diagnostics, target-fielding strategies, and data storage methods cannot support this pace of operation. Therefore, established experimental paradigms must change for the community to progress toward rep-rated operation.

The intersection of race and sex on the clinical and cognitive progression of multiple sclerosis.

Objective: Black populations show increased incidences of diagnosis, worse disease severity, and earlier likelihood of mortality due to MS. Clinical outcomes are also linked to biological sex and as with Black individuals, MS characteristics between sexes have also shifted overtime. This study examined whether clinical disease progression differed by race and sex for patients with MS.

Laboratory evidence of the nonresonant streaming instability in the formation of quasiparallel collisionless shocks at high Alfvénic Mach number.

We present an experimental investigation of the formation stage of a collisionless shock when the flow velocity is aligned with an ambient magnetic field utilizing laser-driven, super-Alfvénic plasma flows. As the flows interact, electromagnetic streaming instabilities develop. Proton deflectometry is used to visualize these electromagnetic fluctuations indicating the development of the ion-Weibel instability and the nonresonant instability.