Publications by authors named "M Mantero"

Sex and gender differences significantly influence lung parenchyma development, beginning as early as the embryonic stages of human life. Although this association is well known in the clinical manifestations of some relevant pulmonary diseases, there is less data available regarding their effects on cell biological programmes across different stages of body development. A deep understanding of these mechanisms could help in defining preventive strategies tailored to a fully personalised approach to respiratory medicine.

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Neuromuscular diseases (NMDs) comprise a heterogeneous group of conditions characterized by extreme progressive muscle weakness leading to respiratory failure. Noninvasive mechanical ventilation (NIV) has emerged as a cornerstone in the management of respiratory complications associated with NMDs. This review aims to elucidate the role of NMV in respiratory function, improving quality of life, and prolonging survival in individuals with NMD.

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Sporotrichosis is a subacute to chronic subcutaneous mycosis caused by dimorphic fungi of the Sporothrix spp. complex. It is considered the most frequent subcutaneous mycosis in Latin America and predominates in tropical areas.

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Objectives: Vasoactive drugs have exhibited clinical efficacy in addressing pulmonary arterial hypertension, manifesting a significant reduction in morbidity and mortality. Pulmonary hypertension may complicate advanced interstitial lung disease (PH-ILD) and is associated with high rates of disability, hospitalisation due to cardiac and respiratory illnesses, and mortality. Prior management hinged on treating the underlying lung disease and comorbidities.

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Article Synopsis
  • The study focused on comparing hospitalized vaccinated and non-vaccinated patients diagnosed with SARS-CoV-2 in three major hospitals in Northern Italy, investigating their clinical characteristics and outcomes.
  • Data analysis highlighted that vaccinated patients, despite having more serious underlying health issues, generally had milder COVID-19 symptoms and required less intensive care compared to non-vaccinated patients.
  • No significant difference in intra-hospital mortality rates was found between the two groups, indicating vaccination effectively reduces the likelihood of ICU admission but does not significantly impact overall survival rates in the hospital.
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