SERS profiling of blood serum filtrate components from patients with type II diabetes using 100 kDa filtration devices.

Blood carries some of the most valuable biomarkers for disease screening as it interacts with various tissues and organs in the body. Human blood serum is a reservoir of high molecular weight fraction (HMWF) and low molecular weight fraction (LMWF) proteins. The LMWF proteins are considered disease marker proteins and are often suppressed by HMWF proteins during analysis.

Role of Next-Generation Sequencing in the Treatment of Metastatic Apocrine Carcinoma: A Rare Entity.

Primary apocrine adenocarcinoma, a rare malignancy, is an aggressive tumor rarely reported. It has diagnostic and treatment challenges as it is difficult to distinguish it from metastases due to breast carcinoma. Currently, no data are available for the use of next-generation sequencing to identify the possibility of targeted therapies for metastatic disease.

The efficacy of curcumin-piperine supplementation in patients with nonproliferative diabetic retinopathy: An optical coherence tomography angiography-based randomized controlled trial.

Background: Diabetic retinopathy (DR) is one of the complications of diabetes. This study was conducted to investigate the effect of curcumin-piperine on laboratory factors and macular vascular in DR.

Materials And Methods: The present study was a randomized, placebo-controlled, double-blind, parallel-arm clinical trial that was conducted on 60 patients with DR aged 30-65 years.

Surface-enhanced Raman spectroscopy for the characterization of filtrate portions of blood serum samples of myocardial infarction patients using 30 kDa centrifugal filter devices.

Myocardial infarction (MI) is the leading cause of death and disability worldwide. It occurs when a thrombus forms after an atherosclerotic plaque bursts, obstructing blood flow to the heart. Prompt and accurate diagnosis is crucial for improving patient survival.

Surface-enhanced Raman spectroscopy for the rapid identification of fosfomycin resistant and sensitive strains of E. coli.

Development of rapid detection and discrimination technique for the antibiotic resistant and sensitive bacterial strains is required for this purpose, Surface-enhanced Raman spectroscopy (SERS) technique is considered to have great potential. To develop a fast and sensitive detection and discrimination methodology based on SERS technique along with chemometric tools for the differentiation among fosfomycin sensitive and resistant Escherichia coli (E. coli) strains.