Fluorescein angiography of iris juvenile xanthogranuloma.

A 3-year-old boy was referred because of the presence of a non-pigmented, highly vascular mass with tapioca appearance involving the superior portion of the left iris. Iris fluorescein angiography revealed early hyperfluorescence of the iris tumor with diffuse, intense late leakage of dye throughout the entire iris, not just in the region of the tumor. Cytopathologic examination revealed Touton giant cells and the presence of histiocytes, confirming the diagnosis of iris juvenile xanthogranuloma.

Fine-needle aspiration biopsy of iris tumors in 100 consecutive cases: technique and complications.

Objective: To evaluate the technique and complications of fine-needle aspiration biopsy (FNAB) for iris tumors.

Design: Retrospective, nonrandomized, single-center case series.

Participants: One hundred eyes of 100 patients with diagnostically challenging iris tumors evaluated with FNAB.

Management of choroidal metastases from breast carcinomas using aromatase inhibitors.

Purpose Of Review: The outcome of patients diagnosed with uveal metastases from breast carcinoma, all of whom were treated with one of the new generation of hormone therapies named aromatase inhibitors, is reported.

Recent Findings: Charts of all patients with uveal metastases from breast cancer seen at Wills Eye Hospital between 1995 and 2005 are reviewed. Seventeen patients were diagnosed with uveal metastases from estrogen-receptor-positive breast cancer and subsequently treated with one of the aromatase inhibitors (anastrozole, letrozole, exemestane).