Publications by authors named "M Manin"

Article Synopsis
  • * Researchers examined the brain connectivity of 92 infants, comparing those born to mothers with a history of CM to those without, assessing how this might differ based on the infant's sex.
  • * Results showed that male infants from maltreated mothers had increased fronto-limbic connectivity, linked to later behavioral issues, while no significant effects were found in female infants, indicating a need for more studies on these intergenerational effects.
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New weapons to fight cancer are constantly needed. Among chemotherapeutics, anti-cancer metal-drugs have enjoyed a long and successful history since the discovery of the benchmark cisplatin. Advances in metal-drug discovery have motivated chemists to build plethora of complex structures.

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Prostaglandin F(2alpha) (PGF(2alpha)), represses ovarian steroidogenesis and initiates parturition in mammals but its impact on adrenal gland is unknown. Prostaglandins biosynthesis depends on the sequential action of upstream cyclooxygenases (COX) and terminal synthases but no PGF(2alpha) synthases (PGFS) were functionally identified in mammalian cells. In vitro, the most efficient mammalian PGFS belong to aldo-keto reductase 1B (AKR1B) family.

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