Publications by authors named "M Manikandan"

Cancers are a class of disorders that entail uncontrollably unwanted cell development with dissemination. One in six fatalities globally is attributed to cancer, a global health issue. The analysis of the entire DNA sequence and how it expresses itself in tumor cells is known as cancer genomics.

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The epitome of periodontal plastic surgical procedures is to achieve coverage of the denuded root surface and flawless esthetics. Connective tissue graft (CTG) along with coronally advanced flap (CAF) is the most frequent approach, which is considered a gold standard remedy. The procurement of CTG requires a second surgical site morbidity.

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Nanostructured materials incorporating transition metal sulfides have demonstrated considerable potential across various applications, particularly in the realms of energy production and storage. Sulfide-based material preparation is a challenging and costly procedure that requires a high temperature and reducing atmosphere. This work reports that manganese cobalt sulfide (MCS) and reduced graphene oxide composite manganese cobalt sulfide (rMCS) were successfully prepared through a hydrothermal method.

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Article Synopsis
  • * A new platinum-based anticancer drug was identified that not only overcomes resistance to cisplatin (a common chemotherapeutic) but also has low toxicity on the kidneys.
  • * This drug was found to significantly reduce blood vessel formation in zebrafish and demonstrated its ability to kill cancer cells through specific processes known as necroptosis and paraptosis, highlighting its potential as an effective cancer treatment.
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Objectives: To examine dentoalveolar changes following intrusion of maxillary incisors with one or two anterior miniscrews in subjects with gummy smile and deep bite.

Materials And Methods: Forty-three subjects were selected and divided into two groups: group I (22 subjects: 15 women, 7 men; mean age 30 ± 10 years) received one miniscrew between the upper central incisors, and group II (21 subjects: 16 women, 5 men; mean age 30 ± 10 years) received two miniscrews between the canines and lateral incisors. Dentoalveolar parameters, including amount of intrusion, root resorption, incisor inclination, alveolar bone thickness, and buccal alveolar crest height (cementoenamel junction to labial alveolar crest), were evaluated using cone-beam computed tomography scans obtained before and after intrusion.

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