Publications by authors named "M Manfredini"
Article Synopsis
- The incidence of metabolic syndrome (MS) has risen in developed countries due to lifestyle choices, combining various health issues that heighten the risk of diabetes and heart diseases.
- Chronic low-grade inflammation, largely driven by obesity and an increase in visceral fat, plays a vital role in the development of MS and is now recognized as a significant cardiovascular risk factor.
- Psoriasis, an inflammatory skin condition, may be linked to metabolic disorders; improving diet and exercise can enhance psoriasis treatment outcomes, highlighting the potential of gut microbiota as a target for therapeutic interventions.
Article Synopsis
- Difficult-to-treat areas in psoriasis traditionally included the face, scalp, and genitals, but recent findings highlight the legs as a new challenging site, often affected even with biologic therapies.
- The study evaluated the effectiveness of the biologic drug risankizumab on leg psoriasis compared to other body areas in patients undergoing this treatment.
- Results showed that legs improved more slowly than other sites during initial weeks, but risankizumab is still considered effective for leg psoriasis despite this delayed response.
Purpose: Even today, melanoma is a highly aggressive neoplasm with a high mortality rate. The nodular type is very aggressive and has cerebroid nests of melanocytes (CNMs) at the growth edge, morphologically similar to the poorly differentiated neoplastic epithelial cell clusters described in colorectal, breast, and endometrioid endometrial cancers.
Patients And Methods: We selected 25 nodular melanomas (NMs) with known molecular profiles, of which the entire paraffin-embedded lesion was available.
Dental implant fractures pose a significant challenge to long-term treatment success. This systematic review aims to comprehensively examine the clinical factors influencing dental implant fractures (IFs). Furthermore, strategies to choose the right type of implant and prevent this complication are addressed.
View Article and Find Full Text PDF