Relationship between EZH2 expression and prognosis of patients with hepatocellular carcinoma using a pathomics predictive model.

Background: Enhancer of zeste 2 polycomb repressive complex 2 subunit (EZH2) is overexpressed in hepatocellular carcinoma, promoting tumorigenesis and correlating with poor prognosis. Traditional histopathological examinations are insufficient to accurately predict hepatocellular carcinoma (HCC) survival; however, pathomics models can predict EZH2 expression and HCC prognosis. This study aimed to investigate the relationship between pathomics features and EZH2 expression for predicting overall survival of patients with HCC.

Hole-Transporting Materials Based on a Fluorene Unit for Efficient Optoelectronic Devices.

Solution-processable hole-transporting materials (HTMs) that form highly soluble films and thermally stable amorphous states are essential for advancing optoelectronic devices. However, the currently commercialized HTM, N,N-bis(3-methylphenyl)-N,N0-bis(phenyl)benzidine (TPD), exhibits poor solubility and limited carrier transport when spin-coated into thin films. Herein, to address these issues, a fluorenyl group was ingeniously incorporated into a series of molecules structurally similar to TPD.

Endoscopic treatment of complications after bariatric surgery - overview of issues and retrospective analysis of our own results.

Bariatric and metabolic surgery is the most invasive but also the most effective treat-ment for severe obesity and associated comorbidities. The most common procedures performed are laparoscopic sleeve gastrectomy and Roux-Y gastric bypass. Postoperative complications occur in 4-10% cases.

B-Lines in the Assessment of Interstitial Lung Disease Associated with Scleroderma: The Role of Handheld Devices.

: Timely detection and aggressive management of interstitial lung disease (ILD) in systemic sclerosis (SSc) are essential to improving outcomes and reducing risks of irreversible lung injury. : to explore the usefulness of an ultraportable ultrasound device for the management of SSc-related ILD and to compare it with clinical and instrumental data. : A total of 19 consecutive SSc patients underwent a comprehensive pulmonary evaluation: clinical, pulmonary function tests (PFTs) (spirometry, DLCO), lung CT (1.