Publications by authors named "M Malova"
Early extubation is considered to be beneficial for pre-term neonates. On the other hand, premature extubation can cause lung derecruitment, compromised gas exchange, and need for reintubation, which may be associated with severe brain injury caused by sudden cerebral blood flow changes. We used near infrared spectroscopy (NIRS) to investigate changes in cerebral oxygenation (rScO) and fractional tissue oxygen extraction (+) after extubation in pre-term infants.
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- Extra-uterine growth restriction (EUGR) is linked to poor development outcomes in very-low-birth-weight neonates, with a study of 288 patients examining various factors influencing growth and development.
- The research found that a higher weight z-score at 6 months positively impacts overall developmental quotient (DQ) at 2 years, while EUGR at that age correlates with poorer performance across multiple developmental areas.
- The findings highlight the importance of improved post-discharge nutrition and family education to support better growth and development in vulnerable infants.
Background: During the last decades, severe brain lesions affecting very low birth weight (<1500 gr, VLBW) infants were gradually substituted by milder lesions with debatable prognoses.
Objective: The objective of this study is to define type, frequency and 3 years of neurodevelopmental outcome of prematurity-related brain lesions in a modern cohort of VLBW infants.
Methods: VLBW infants admitted to our NICU in 5 years period with brain MRI at term-equivalent age were included.
Objectives: To evaluate punctate white matter lesion (PWML) influence in preterm infants on the long-term neurodevelopmental outcome (NDO).
Methods: PubMed and EMBASE were searched from January 1, 2000, to May 31, 2021. Studies were included in which PWML in preterm infants on MRI around term-equivalent age (TEA) and NDO at ≥12 months were reported.
Background: Very low birth weight infants are at risk of developing periventricular white matter lesions. We previously reported high blood adenosine levels in premature infants and infants with low birth weight. We asked whether blood adenosine levels could be related to the vulnerability of the maturing white matter to develop lesions.
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