Predicted changes in future precipitation and air temperature across Bangladesh using CMIP6 GCMs.

Understanding spatiotemporal variability in precipitation and temperature and their future projections is critical for assessing environmental hazards and planning long-term mitigation and adaptation. In this study, 18 Global Climate Models (GCMs) from the most recent Coupled Model Intercomparison Project phase 6 (CMIP6) were employed to project the mean annual, seasonal, and monthly precipitation, maximum air temperature (Tmax), and minimum air temperature (Tmin) in Bangladesh. The GCM projections were bias-corrected using the Simple Quantile Mapping (SQM) technique.

Differential absorption lidar data acquisition and control system for remote detection of trace chemicals including methane and thiodiglycol.

We report the design and development of a data acquisition and control system for high-speed acquisition of weak, backscattered differential signals and synchronized sequential operation of all subsystems of a tunable, mid-infrared Differential Absorption Lidar (DIAL) system. The presence of a low-level concentration of chemical species results in weak differential return signals. The differential signal also varies dynamically with respect to background atmospheric conditions.

The impact of climate change, population growth and development on sustainable water security in Bangladesh to 2100.

There are concerns that groundwater use for irrigation and for urban water supply is unsustainable in some parts of Bangladesh, particularly in the agriculturally productive northwest region. We use an integrated population - GDP - food - water model to examine water demand to 2100 in Bangladesh in development scenarios relevant to food and water security. The results indicate that irrigation water demand is projected to increase in coming decades, but later in the century it may decrease due to increasing crop yields and a falling population.

Numerical groundwater modelling for studying surface water-groundwater interaction and impact of reduced draft on groundwater resources in central Ganga basin.

Water resources in India's Indo-Gangetic plains are over-exploited and vulnerable to impacts of climate change. The unequal spatial and temporal variation of meteorological, hydrological and hydrogeological parameters has created additional challenges for field engineers and policy planners. The groundwater and surface water are extensively utilized in the middle Gangetic plain for agriculture.

Drug-survival profiling of second-line biologic therapy in rheumatoid arthritis: Choice of another tumour necrosis factor inhibitor or a biologic of different mode of action?

Objectives: To assess the best choice of second-line therapy between tumour necrosis factor-inhibitor (TNFi) and biologics of different-mode-of-action (BDMA-rituximab/tocilizumab/abatacept) in rheumatoid arthritis (RA) by evaluating drug-survival following discontinuation of the first-line TNFi.

Methods: This retrospective drug-survival study was performed across two different hospitals by conventional-statistics and machine-learning approach.

Results: From a total of 435 patients, 213 (48.