Publications by authors named "M Mainguy"
Assessing the Risk of Relapse After In Vitro Fertilization in Women With Multiple Sclerosis.
Neurol Neuroimmunol Neuroinflamm
March 2025
Background And Objectives: Older studies reported an increased risk of relapse after in vitro fertilization (IVF) in women with multiple sclerosis (MS), which has not been confirmed by more recent works. All these studies had several limitations, such as small sample sizes, absence of a control population, or lack of neurologic validation of the relapses. The aim of this study was to determine the risk of relapse after IVF in women with MS.
View Article and Find Full Text PDFBackground: France is among the countries with high prevalence of multiple sclerosis (MS). The most recent estimates are from 2012 and need to be updated because MS prevalence has increased worldwide.
Objective: To estimate MS prevalence in France on December 31, 2021 and to describe the characteristics of the French MS population using data from the French national health insurance database (SNDS).
Article Synopsis
- Illicit substance use at music festivals has changed over the years, leading to the implementation of the OCTOPUS survey to better understand drug use patterns among attendees.
- Conducted between July 2017 and July 2018 at 13 festivals in France, the survey collected data from 383 participants to analyze drug use prevalence and classify user profiles.
- The results showed that 82% of participants reported drug use, with two main profiles identified: "no/low polysubstance use," primarily using classic stimulants, and "moderate/extensive polysubstance use," which included a broader range of substances, indicating the need for improved harm reduction strategies.
Introduction: Many studies have investigated pregnancy in women with multiple sclerosis (MS). However, no study has measured prenatal healthcare utilization in women with MS or adherence to follow-up recommendations to improve antenatal care quality. A better knowledge of the quality of antenatal care in women with MS would help identify and better support women with insufficient follow-up.
View Article and Find Full Text PDFBackground And Objectives: Several studies have shown an increased risk of relapse after in vitro fertilization (IVF) in women with multiple sclerosis (MS), especially when a gonadotrophin-releasing hormone (GnRH) agonist stimulation protocol was used. Our objective was to investigate the risk of relapse after IVF in women with MS, overall and according to stimulation protocol (GnRH agonists vs antagonists), using data from the French national health insurance database.
Methods: This retrospective cohort study included all women with MS who have benefited from IVF between January 1, 2010, and December 31, 2015, in France.