Adjusting the apnea-hypopnea index in children with a low percentage of REM sleep and its potential impact on OSA diagnosis and severity.

A decrease in REM time during polysomnography (PSG) in patients with obstructive sleep apnea (OSA) can result in underestimation of apnea hypopnea index (AHI). We propose adjusting AHI to normalized REM% in subjects with REM% ≤15% to avoid under diagnosis of OSA. All children who completed diagnostic PSG from 2016 to 2023 with REM% of ≤ 15% of total TST were selected for adjustment.

MHC-related protein 1-restricted recognition of cancer via a semi-invariant TCR-α chain.

The T cell antigen presentation platform MR1 consists of 6 allomorphs in humans that differ by no more than 5 amino acids. The principal function of this highly conserved molecule involves presenting microbial metabolites to the abundant mucosal-associated invariant T (MAIT) cell subset. Recent developments suggest that the role of MR1 extends to presenting antigens from cancer cells, a function dependent on the K43 residue in the MR1 antigen binding cleft.

Point-of-care optical spectroscopy platform and ratio-metric algorithms for rapid and systematic functional characterization of biological models .

Significance: Cellular metabolism is highly dynamic and strongly influenced by its local vascular microenvironment, gaining a systems-level view of cell metabolism is essential in understanding many critical biomedical problems in a broad range of disciplines. However, very few existing metabolic tools can quantify the major metabolic and vascular parameters together in biological tissues with easy access.

Aim: We aim to fill the technical gap by demonstrating a point-of-care, easy-to-use, easy-to-access, rapid, systematic optical spectroscopy platform for metabolic and vascular characterizations on biological models to enable scientific discoveries to translate more efficiently to clinical interventions.

Examining nursing students' awareness of various medical errors during clinical internships to enhance patient safety: A multi-center cross-sectional study.

Background: Patient safety is a global concern within health facilities, primarily attributed to medical errors, constituting a significant global public health issue. Patients experiencing medication errors face serious problems, with increasing mortality rates and escalating hospital costs.

Aim: The study aims to examine nursing students' awareness of various medical errors during their clinical internships at Al- Ahsa, identifying types of errors to enhance patient safety.

Socio-Demographic Characteristics, Clinical Presentations and Treatment Outcome of RT-PCR Positive Covid-19 Patients of Mymensingh Region.

Coronavirus disease-2019 (Covid-19) caused by the virus SARS-CoV 2 is a major health problem across the globe currently. Bangladesh is also defying this highly infectious disease with an exponentially rising number of cases across the country. This study was designed to observe the socio-demographic characteristics, clinical presentation and treatment outcome of Covid-19 cases in Bangladesh.