Insights into voluntary plasma donation: A study of motivators and obstacles.

Background: Plasma-derived medicines (PDMs) are essential for treating various disorders and require large volumes of human plasma. The debate on voluntary and compensated plasma donation continues, while WHO advocating for voluntary donations. This study examines factors influencing plasma donation, focusing on the effectiveness of voluntary donation and identifying key motivators and barriers.

Development and validation of the self-regulation of blood donation scale for blood donors.

Background: Because knowledge of blood donor motivation is crucial in guiding recruitment and retention efforts, the present study aimed at developing and validating a new scale as a multidimensional measure of blood donation motivation from the perspective of the self- determination theory.

Methods: This study was conducted in three phases from September 2022 to May 2023. The first phase involved developing a draft scale based on a literature review.

Circular RNAs in glioblastoma.

Glioblastoma multiforme (GBM) is the most malignant and common form of brain cancer in adults. The molecular mechanisms underlying GBM progression and resistance are complex and poorly understood. Circular RNAs (circRNAs) are a new class of non-coding RNAsformed by covalently closed loopstructures with no free ends.

Circular RNAs in laryngeal cancer.

Laryngeal cancer remains a significant global health concern, with poor prognosis for advanced-stage disease highlighting the need for novel diagnostic, prognostic, and therapeutic approaches. Circular RNAs (circRNAs), a class of covalently closed non-coding RNAs, have emerged as important regulators of gene expression and cellular processes in various cancers, including laryngeal cancer. This review summarizes the current understanding of circRNAs in laryngeal cancer, covering their biogenesis, regulatory mechanisms, and potential clinical applications.