Publications by authors named "M Madhar"

Tarsal tunnel syndrome is a multifaceted condition caused by the compression or lesion of the posterior tibial nerve (PTN) that passes through a retromalleolar osteofibrous canal, the so-called tarsal tunnel. It has multiple etiologies, including peripheral nerve tumors, which must be suspected when this syndrome is resistant to medical treatment and infiltrations. We here report the original case of a 15-year-old girl presenting with tarsal tunnel syndrome revealing neurofibroma of the PTN, misdiagnosed as plantar fasciculitis and S1 radiculopathy.

View Article and Find Full Text PDF

Necrotizing fasciitis (NF) is both a limb-and life-threatening disease that affects skin, hypodermis as well as superficial fascia and deep fascia by rapidly progressive necrosis. Although this serious infection frequently occurs in the extremities, upper limb NF is a rare clinical presentation. The present study attempted to evaluate the clinical profiles, paraclinical findings, treatment modalities, outcomes and predictors of morbidity and mortality in patients with NF of the upper extremity.

View Article and Find Full Text PDF

Introduction: complete joint fractures of the lower end of the humerus are rare and severe injuries in adults, affecting the functional prognosis of a narrow and complex joint such as the elbow. Multiple therapeutic options are available, but osteosynthesis is widely used provided that it can recover stable, mobile, and painless joint. The purpose of our study was to describe the epidemiological, clinical, radiological and therapeutic features of these fractures, as well as to evaluate functional outcomes in our patients.

View Article and Find Full Text PDF

Multiple pharmacogenetic studies investigated the effectiveness of methotrexate. However, due to the use of nonvalidated outcomes, lack of validation or conflicting results it remains unclear if genetic markers can help to predict response to MTX treatment. Therefore, a systematic review was performed.

View Article and Find Full Text PDF