Publications by authors named "M Madar"

Article Synopsis
  • * A total of 62 healthy dogs and 13 CKD-affected dogs were analyzed, with findings showing no sex differences; however, age was a factor, with older dogs (>6 years) having higher NAG/creatinine (Cr) ratios compared to younger ones (2-6 years).
  • * The lowest NAG/Cr ratio was found in dogs with CKD stage 2, and while the study established a reference range for NAG/Cr, no significant correlations
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The species is a bacterium extensively used in the dairy industry. This bacterium is Generally Recognized as Safe and was added to the European Food Safety Authority's Qualified Presumption of Safety list. The major functions of this species in dairy fermentation are the production of lactic acid from lactose, citric acid fermentation, and the hydrolysis of casein.

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Article Synopsis
  • Alpha klotho is being studied as a potential biomarker for chronic kidney disease (CKD) and kidney-related disorders, but its relationship with kidney function has mixed findings.
  • The study focused on how factors like age, sex, and breed affect urinary alpha klotho levels in dogs with early CKD, finding higher levels in older dogs and German Shepherds compared to Belgian Shepherds.
  • It established a reference range for urinary alpha klotho to creatinine ratio in healthy dogs and noted that lower alpha klotho levels in CKD stage 2 dogs indicate the need for considering age in future studies.
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Article Synopsis
  • * Results showed that urinary uromodulin levels correlated with kidney disease markers in stage 1 CKD and were significantly lower in dogs at stage 2, particularly in Belgian shepherds compared to German shepherds.
  • * The research suggests that urinary uromodulin may be a better indicator of CKD than serum uromodulin, but further studies with more subjects are needed to confirm its effectiveness as an early-stage disease marker.
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We present the design and synthesis of four new schiff bases viz., two each of phenothiazine and coumarin derivatives. The structures were proposed based on FT-IR, H NMR, C NMR and mass spectral data.

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