Publications by authors named "M Machouart"
Article Synopsis
- * This study analyzed cases of C bantiana infections in France and its territories, involving patients who were diagnosed through a comprehensive surveillance program, focusing on survival rates and the presence of central nervous system (CNS) involvement.
- * Out of 23 patients identified from 2002 to 2022, 65% had CNS involvement, with a notable increase in cases reported in 2022, indicating a possible correlation with environmental factors like rising temperatures.
Article Synopsis
- * Most TC cases were linked to the anthropophilic fungus Trichophyton tonsurans, which accounted for 32.6% of cases, while zoophilic species like M. canis were less common, indicating a shift towards human-associated infections.
- * Diagnosis typically involves traditional methods such as microscopy and culture, but advanced techniques like MALDI-TOF mass spectrometry and molecular identification have been adopted in many labs to enhance accuracy.
Article Synopsis
- Intra-abdominal candidiasis (IAC) is challenging to diagnose in critically ill patients, often leading to excessive antifungal treatments; current markers like serum and peritoneal 1.3-beta-D-glucan (sBDG and pBDG) have shown inconsistent results in identifying IAC due to varying patient populations.
- This study investigated a high-risk population of critically ill patients undergoing abdominal surgery, aiming to determine the prevalence of IAC and the effectiveness of sBDG and pBDG in its diagnosis, finding a 44% prevalence rate among 199 included patients.
- Results showed that pBDG levels were significantly higher in patients with IAC compared to those without, suggesting pBDG could be
Background: The understanding of high mortality associated with intra-abdominal candidiasis (IAC) remains limited. While Candida is considered a harmless colonizer in the digestive tract, its role as a true pathogen in IAC is still debated. Evidence regarding Candida virulence in the human peritoneal fluid are lacking.
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