Publications by authors named "M Macedo"

Cervical and lower back pain are classic reasons for patients to seek care in the emergency department (ED). However, in rare instances, they signal serious underlying conditions, posing a significant diagnostic challenge. A 72-year-old male with history of lumbar spine surgery many years ago presented to the ED with neck pain for the last five days as well as bilateral lower limb weakness and feet paresthesia.

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This study aimed to assess the immediate effects of transcutaneous spinal direct current stimulation (tsDCS) on pain outcomes, measured using the visual analog scale (VAS) and pressure pain thresholds in a cohort of 55 participants experiencing chronic pain using a controlled, randomized trial with 55 participants allocated into 2 groups: 2 mA and 0.5 mA of tsDCS for 20 min. Anodal stimulation was applied on the 12th thoracic vertebra, with the cathode positioned on the 7th cervical vertebra.

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The integration of machine learning into the domain of radiomics has revolutionized the approach to personalized medicine, particularly in oncology. Our research presents RadTA (RADiomics Trend Analysis), a novel framework developed to facilitate the automatic analysis of quantitative imaging biomarkers (QIBs) from time-series CT volumes. RadTA is designed to bridge a technical gap for medical experts and enable sophisticated radiomic analyses without deep learning expertise.

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Article Synopsis
  • The study investigates the relationship between CEACAM1 levels and insulin metabolism in individuals with Type 2 diabetes and obesity.
  • Findings show that as insulin resistance and hyperinsulinemia increase, CEACAM1 levels decrease, particularly in those with prediabetes and Type 2 diabetes.
  • The results suggest that measuring circulating CEACAM1 could serve as a useful biomarker for assessing metabolic health and insulin clearance.
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