Publications by authors named "M Maaroos"

Purpose: Cardiac surgery and conventional extracorporeal circulation (CECC) impair the bioavailability of drugs administered by mouth. It is not known whether miniaturized ECC (MECC) or off-pump surgery (OPCAB) affect the bioavailability in similar manner. We evaluated the metoprolol bioavailability in patients undergoing CABG surgery with CECC, MECC, or having OPCAB.

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Article Synopsis
  • New onset postoperative atrial fibrillation (POAF) after cardiac surgery increases the risk of thromboembolic complications and requires effective anticoagulation treatment for better outcomes.
  • A study involving 519 cardiac surgery patients found that 34% experienced POAF, with higher mortality and major adverse clinical events in this group compared to those without POAF.
  • The findings suggest that initiating an anticoagulation protocol immediately after POAF may improve long-term outcomes for these patients.
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Background And Aims: Atrial fibrillation is a common arrhythmia after cardiac surgery. It increases morbidity, length of hospital stay, and costs of operative treatment. Beta-blockers, sotalol, amiodarone, corticosteroids, and biatrial pacing have been shown to be efficient in the prevention of postoperative atrial fibrillation.

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Background And Aims: Atrial fibrillation (AF) is the most common arrhythmia after coronary artery bypass surgery (CABG). Intravenous metoprolol and biatrial pacing have been reported to be effective in AF prophylaxis after cardiac surgery. The purpose of this trial was to compare the efficacy of intravenous metoprolol versus biatrial pacing combined with oral metoprolol in the prevention of AF after CABG.

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