Publications by authors named "M M el-Sageyer"
An echovirus 11' (prime) virus caused an epidemic in Hungary in 1989. The leading clinical form of the diseases was myocarditis. Hemorrhagic hepatitis syndroms were also caused, however, with lethal outcome in 13 newborn babies.
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- Echovirus 11' strains linked to a haemorrhagic syndrome epidemic in Hungarian obstetrics caused severe carditis, leading to the death of 13 newborns and revealed a lack of maternal immunity.
- The use of a monovalent oral poliovirus vaccine effectively controlled the epidemic within two weeks, although 20% of vaccinated infants showed seroconversion to echovirus 11' without symptoms.
- Genetic analysis of echovirus 11' showed distinct changes in the 5'-end and P1 region compared to prototype strains, indicating genetic evolution prior to the outbreak.