Publications by authors named "M M Wynn"
The sleeve gastrectomy (SG) often requires conversion to Roux-en-Y gastric bypass (RYGB) due to gastroesophageal reflux disorder (GERD). Many postbariatric patients seek body-contouring surgery such as abdominoplasty to remove unwanted skin and fat. Although the number of abdominoplasties performed in postbariatric patients is increasing each year, the number of conversion surgeries is increasing in accordance.
View Article and Find Full Text PDFThere are currently no prophylactic vaccines licensed to protect against Lassa fever caused by Lassa virus (LASV) infection. The Emergent BioSolutions (EBS) vaccine candidate, EBS-LASV, is being developed for the prevention of Lassa fever. EBS-LASV is a live-attenuated recombinant Vesicular Stomatitis Virus (rVSV)-vectored vaccine encoding the surface glycoprotein complex (GPC) from LASV and has two attenuating vector modifications: a gene shuffle of the VSV N gene and a deletion of the VSV G gene.
View Article and Find Full Text PDFBackground: Global challenges arise from infectious diseases which represent significant challenges to the provision of healthcare, requiring efficient management procedures to limit transmission. Evaluating current outbreak management processes within UK healthcare services is essential for identifying strengths, weaknesses, and potential improvements.
Objectives: This study aimed to assess infection prevention and control (IPC) practitioners' access to outbreak management (OM) data.
Background: Restrictions during the COVID-19 pandemic influenced a shift to same-day discharge in bariatric surgery. Current studies show conflicting findings regarding morbidity and mortality. We aim to compare outcomes for same-day discharge versus admission after bariatric surgery.
View Article and Find Full Text PDFArticle Synopsis
- The cumulus-oocyte complex (COC) is important for ovulation, with its migratory abilities influenced by the expression of various proteases and their inhibitors.
- In rats, human chorionic gonadotropin (hCG) significantly boosts the expression of specific proteases and inhibitors during ovulation, which can also be replicated with forskolin and ampiregulin in cultured COCs.
- Comparative studies between rat and human COCs show differences in protease expression, suggesting that these enzymes are crucial for the migratory behavior of the COC at the time of ovulation.